穿膜肽修饰

将药物分子引入细胞的过程一直是科研工作者面临的一个重要挑战，然而，穿膜肽(CPPs)却有穿过细胞膜的能力，但是又不需要依靠膜受体。穿膜肽通常由10-30个带正电荷的氨基酸组成。穿膜肽(CPPs)可以将具有生物活性的药物分子传递到细胞内部。我们可以将我们想要的药物分子结合到穿膜肽(CPPs)上，然后传递到细胞内的目标靶点，以此克服细胞膜带来的通过障碍。穿膜肽(CPPs)作为非病毒类穿膜载体受到了科研工作者的普遍欢迎。虽然他们成功的将其应用于转运各种不同大小的药物分子(质粒，多肽，蛋白，纳米粒子等)，但是最快速的还是应用在寡聚核苷酸(ONs)的转运上。
点击下载穿膜肽列表

常用穿膜肽

  • 名称
  • 序列
  • 2
  • DSLKSYWYLQKFSWR (Kondo et al. 2012)
  • 18A
  • DWLKAFYDKVAEKLKEAF (Datta et al. 2000)
  • α1H
  • KSKTEYYNAWAVWERNAP (Gomarasca et al. 2017)
  • α2H
  • GNGEQREMAVSRLRDCLDRQA (Gomarasca et al. 2017)
  • A22p
  • HTPGNSNKWKHLQENKKGRPRR (Shin et al. 2014)
  • Ac-18A-NH2
  • DWLKAFYDKVAEKLKEAF) (Wimley and White 2000)
  • aCPP
  • Typical sequence R9GPLGLAGE8 (Li et al 2015)
  • AdVpVI(33-55)
  • Ac-GAFSWGSLWSGIKNFGSTVKNYG (Murayama et al. 2016)
  • AIP6
  • RLRWR (Wang et al. 2011)
  • all-d DsC18
  • Glrkrlrkfrnkikek (Bergmann et al. 2017)
  • αgliadin(31-43)
  • LGQQQPFPPQQPY (Paolella et al. 2018)
  • Alyteserin-2a
  • ILGKLLSTAAGLLSNL (Conlon et al. 2013)
  • ANG
  • TFFYGGSRGKRNNFKTEEY (Demeule et al. 2008)
  • ApoE(141–150)
  • Ac-LRKLRKRLLRX-Bpg-G (Shabanpoor et al. 2017)
  • ApoE-derived
  • Ac-LRKLRKRLLR (Tailhades et al. 2017)
  • Arf(1-22)
  • MVRRFLVTLRIRRACGPPRVRV (Johansson et al. 2008)
  • AT1002
  • FCIGRL (Gopalakrishnan et al. 2009)
  • AT1AR(304-318)
  • FLGKKFKKYFLQLLK (Östlund et al. 2005)
  • Bac7
  • RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPL (Sadler et al. 2002)
  • BGPC7-FHV
  • RRRRNRTRRNRRRVR-RRFYGPV (Wongso et al. 2017)
  • Bim
  • EIWIAQELRRIGDEFNAYYARLLC (Kim et al. 2017)
  • BP16
  • KKLFKKILKKL (Soler et al. 2014)
  • BP100
  • KKLFKKILKYL (Eggenberger et al. 2009)
  • BPP13a
  • GGWPRPGPEIPP (Sciani et al. 2017)
  • bPrPp(1-30)
  • MVKSKIGSWILVLFVAMWSDVGLCKKRPKP (Magzoub et al. 2006)
  • BR2
  • RAGLQFPVGRLLRRLLR (Lim et al. 2013)
  • Buforin II
  • TRSSRAGLQFPVGRVIIRLLRK (Park et al.1998)
  • Buforin IIb
  • RAGLQFPVG[RLLR]3 (Lee et al. 2008)
  • C6M1
  • RLWRLLWRLWRRLWRLLR (Jafari et al. 2014)
  • C105Y
  • CSIPPEVKFNKPFVYLI (Rhee and Davis 2006)
  • CADY
  • GLWRALWRLLRSLWRLLWRA cycteamide (Crombez et al. 2009a)
  • CAR
  • CARSKNKDC (Toba et al. 2014)
  • CA-Tat
  • KWKLFKKYGRKKRRQRRR (Lv et al. 2017)
  • CB5005 M
  • KLKLALALALA (Zhang et al. 2016)
  • CDB3
  • REDEDEIEW (Issaeva et al. 2003)·
  • CendR
  • RPARPAR (Hu et al. 2014)
  • cFΦR4
  • cyclic F-l-2-naphthylalanine-RRRRQ (Qian et al. 2014)
  • CGKRK
  • CGKRK (Griffin et al. 2017)
  • CIGB-300
  • cyclic CWMSPRHLGTC-Tat (Perera et al. 2012)
  • CIGB-552
  • Ac-HARIKpTFRRlKWKYKGKFW (Fernandez Masso et al. 2013)
  • CLIP6
  • KVRVRVRVpPTRVRERVK (Soudah et al. 2017)
  • CooP
  • ACGLSGLGVA (Hyvonen et al. 2014)
  • CpMTP
  • ARLLWLLRGLTLGTAPRRA (Jain and Chugh 2016)
  • CPNT
  • STSGTGKMTRAQRRAAARRNRA (Qi et al. 2011)
  • CPP1
  • (KFF)3K (Patel et al. 2017)
  • CPP33
  • RLWMRWYSPRTRAYG (Lin et al. 2018)
  • CPP-C
  • PIEVCMYREP (Nakayama et al. 2011)
  • CPPecp
  • NYRWRCKNQN (Fu et al. 2017)
  • C-peptide
  • GPGLWERQAREHSERKKRRRESECKAA (Fan et al. 2016)
  • CRGDK
  • CRGDK (Zhao et al. 2018)
  • Crotamine
  • YKQCHKKGGHCFPKEKICLPPSSDFGKMDCRWRWKCCKKGSG(Rodrigues et al. 2012)
  • cSN50
  • AAVALLPAVLLALLAPVQRKRQKLMP (Torgerson et al. 1998)
  • 65-2CTS
  • CPYVNQRPQKARYRNG (Percipalle et al. 2003)
  • CWR8K
  • CWR8K (Sasaki et al. 2008)
  • CyLoP-1
  • CRWRWKCCKK (Ponnappan et al. 2017)
  • Cyt c(77–101)
  • GTKMIFVGIKKKEERADLIKKA (Howl and Jones 2015)
  • DAG
  • cyclic CDAGRKQKC (Mann et al. 2017)
  • D-JNKI-1
  • RPKRPTTLNLFPQVPRSQDT (Bonny et al. 2001)
  • DK17
  • DRQIKIWFQNRRMKWKK (Bera et al. 2016)
  • DLP
  • ACKTGSHNQCG (Kumar et al. 2015)
  • DMBT1-derived
  • GRVEVLYRGSW and GRVRVLYRGSW (Tuttolomondo et al. 2017)
  • dNP2
  • KIKKVKKKGRK-KIKKVKKKGRK (Lim et al. 2015)
  • DPV3
  • RKKRRRESRKKRRRES (Tacken et al. 2008)
  • DPV1047
  • CVKRGLKLRHVRPRVTRMDV (De Coupade et al. 2005)
  • DRTTLTN
  • DRTTLTN (Gennari et al. 2016)
  • DS4.3
  • RIMRILRILKLAR (Jeong et al. 2014)
  • Dynorphin A
  • YGGFLRRIRPKLKWDNQ (Marinova et al. 2005)
  • EA
  • GLKKLAELAHKLLKLGC (Yang et al. 2014)
  • EB1
  • LIRLWSHLIHIWFQNRRLKWKKK (Lundberg et al. 2007)
  • EF
  • GLKKLAELFHKLLKLGC (Yang et al. 2014)
  • EHB
  • RCSHYTGIRCSHMAATTAGIYTGIRCQHVVL-C6H (Cao et al. 2018)
  • EPRNEEK
  • EPRNEEK (Orihuela et al. 2009)
  • F3**
  • diphosphorylated dipeptide (Miao et al. 2016)
  • G4R9L4
  • G4R9L4 (Ramakrishna et al. 2014)
  • GALA
  • WEAALAEALAEALAEHLAEALAEALEALAA (Li et al. 2004)
  • GeT
  • KIAKLKAKIQKLKQKIAKLK (Rakowska et al. 2014)
  • gH625
  • HGLASTLTRWAHYNALIRAF (Galdiero et al. 2015)
  • Gi3α(346-355)
  • KNNLKECGLY (Jones et al. 2005)
  • Glu-Lys
  • EEEAAKKK (Lewis et al. 2010)
  • GV1001
  • EARPALLTSRLRFIPK (Kim et al. 2016a)
  • GWH1
  • GYNYAKKLANLAKKFANALW (Serna et al. 2017)
  • H2A derived
  • GLFGAIAGFIENGWEGMIDGWYG (Esbjörner et al. 2007)
  • H6R6
  • H6R6 (Sun et al. 2017)
  • H16
  • H16 (Iwasaki et al. 2015)
  • HA2(1-23)
  • H16 (Iwasaki et al. 2015)
  • HAIYPRH
  • HAIYPRH (Shteinfer-Kuzmine et al. 2017)
  • hBD3-3
  • GKCSTRGRKCCRRKK (Lee et al. 2015b)
  • HBP
  • GKRKKKGKGLGKKRDPCLRKYK (Luo et al. 2016)
  • hLF
  • KCFQWQRNMRKVRGPPVSCIKR (Duchardt et al. 2009)
  • Hph-1
  • YARVRRRGPRR (Jung et al. 2011)
  • HR9
  • CH5-R9-H5C (Liu et al. 2013a)
  • Hst5
  • DSHAKRHHGYKRKFHEKHHSHRGY (Luque-Ortega et al. 2008)
  • I1WL5W
  • WKKIWSKIKKLLK (Bi et al. 2014)
  • I4WL5W
  • IKKWWSKIKKLLK (Bi et al. 2014)
  • ID No.2
  • MAAWMRSLFSPLKKLWIRMH (Eudes and Macmillan 2014)
  • IMT-P8
  • RRWRRWNRFNRRRCR (Gautam et al. 2016)
  • INF
  • GLFEAIEGFIENGWEGMIDGWYGC (Pichon et al. 1997)
  • iNGR
  • CRNGRGPDC (Alberici et al. 2013)
  • isl-1
  • RVIRVWFQNKRCKDKK (Kilk et al. 2001)
  • JB9
  • cskc (Basu and Wickstrom, 1997)
  • JB434
  • R9GGLAA-Aib-SGWKH6 (Sangtani et al. 2018)
  • KAFAK
  • KAFAKLAARLYRKALARQLGVAA (Bartlett et al. 2013)
  • KALA
  • WEAKLAKALAKALAKHLAKALAKALKACEA (Wyman et al.1997)
  • Kalata B1
  • polycyclic CGETCVGGTCNTPGCTCSWPVCTRNGLPV (Daly et al.1999)
  • (KFF)3K
  • (KFF)3K (Rownicki et al. 2017)
  • K-FGF
  • AAVLLPVLLAAP (Lin et al. 1995)
  • KH
  • (KH)9 (Chuah et al. 2016)
  • KLA
  • KLAKLAKKLAKLAK (Huang et al. 2017)
  • KLAK
  • KLALKLALKALKAALKLA (Oehlke et al. 1998)
  • KLA-R7
  • KLAKLAKKLAKLAKGGRRRRRRR (Lemeshko, 2013)
  • KP
  • MAPTKRKGSCPGAAPNKKP (Villa-Cedillo et al. 2017)
  • KST peptide
  • STGKANKITITNDKGRLSK (Adachi et al. 2017)
  • L1−6
  • PLILLRLLR (Schmidt et al. 2017)
  • L5a
  • RRWQW (Liu et al. 2016a)
  • L17E
  • IWLTALKFLGKHAAKHEAKQQLSKL (Akishiba et al. 2017)
  • lactoferrampin(265-284)
  • DLIWKLLSKAQEKFGKNKSR (Reyes-Cortes et al. 2017)
  • lactoferricin(17-30)
  • FKCRRWQWRMKKLG (Reyes-Cortes et al. 2017)
  • lactoferrin(19-40)
  • KCFMWQEMLNKAGVPKLRCARK (Duchardt et al. 2009)
  • LAH1
  • KKLALALALALHALALALALKKA (Moulay et al. 2017)
  • LALF(31-52)
  • HYRIKPTFRRLKWKYKGKFW (Yanez et al. 2017)
  • LB
  • FKCRRWQWRMKKLGAPSITCVRRAF) (Liu et al. 2013b)
  • L-CPP
  • LAGRRRRRRRRRK (Liu et al. 2006)
  • LDP-NLS
  • KWRRKLKKLRPKKKRKV (Ponnappan and Chugh, 2017)
  • LE10
  • LELELELELELELELELELE (Antunes et al. 2013)
  • LF chimera
  • FKCRRWQWRMKKLG-K-RSKNKGFKEQAKSLLKWILD(Reyes-Cortes et al. 2017)
  • linTT1
  • AKRGARSTA (Hunt et al. 2017)
  • LK
  • LKKLLKLLKKLLKLAG (Kim et al. 2016b)
  • LL37
  • LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES (Kim et al.2016b)
  • LLIIL
  • LLIIL (Alaybeyoglu et al. 2017)
  • LMWP
  • VSRRRRRRGGRRRR (Chen et al. 2017d)
  • LP-12
  • HIITDPNMAEYL (Kumar et al. 2015)
  • LPAs
  • RCnRCnK (Gupta et al. 2011)
  • LTV
  • LTVSPWY (Chopra 2012)
  • lycosin-I
  • RKGWFKAMKSIAKFIAKEKLKEHL (Tan et al. 2017)
  • Lyp1
  • CGNKRTRGC (Fogal et al. 2008)
  • M918
  • MVTVLFRRLRIRRACGPPRVRV (El-Andaloussi et al. 2007)
  • Maurocalcine
  • GDCLPHLKLCKENKGCCSKKCKRRGTNIEKRCR (Poillot et al.2010)
  • MAP
  • KLALKLALKALKAALKLA (Oehlke et al. 1998)
  • MAP12
  • LKTLTETLKELTKTLTEL (Oehlke et al. 2002)
  • MCoTI-I
  • polycyclic SGSDGGVCPKILQRCRRDSDCPGACICRGNGYCG(Camarero, 2017)
  • MCoTI-II
  • polycyclic CPKILKKCRRDSDCPGACICRGNGYCGSGSDGGV(Huang et al. 2015)
  • MFK
  • MFKLRAKIKVRLRAKIKL (Samuels et al. 2017)
  • Mgpe9
  • CRRLRHLRHHYRRRWHRFRC (Vij et al. 2016a)
  • MitP
  • INLKKLAKL(Aib)KKIL (Howl et al. 2018)
  • m(KLA)-iRGD
  • klaklakklakla-K-GG-iRGD (Qifan et al. 2016)
  • MMGP1
  • MLWSASMRIFASAFSTRGLGTRMLMYCSLPSRCWRK(Pushpanathan et al. 2013)
  • MPER fragment
  • ELDKWASLWNWFDITNWLWYIK (Song et al. 2009)
  • MPG
  • GALFLGFLGAAGSTMGA cysteamide (Morris et al. 1997)
  • MPG
  • GALFLGFLGAAGSTMGASQPKKKRKV cycteamide (Deshayes et al.2005)
  • MPG-8
  • AFLGWLGAWGTMGWSPKKKRK (Crombez et al. 2009b)
  • mRVG
  • YTIWMPENPRPGTPCDIFTKSRGKRASNGGGRRRRRRRRR(Villa-Cedillo et al. 2017)
  • MT23
  • LPKQKRRQRRRM (Zhou et al. 2017)
  • mtCPP1
  • r-Dmt-OF (Cerrato et al. 2015)
  • MTM
  • AAVALLPAVLLALLAP (Fletcher et al. 2010)
  • MTD84
  • AVALVAVVAVA (Lim et al. 2014)
  • MTP
  • MLSLRQSIRFFK (Chuah et al. 2015a, b)
  • MTS
  • KGEGAAVLLPVLLAAPG (Zhao et al. 2001)
  • MTS1
  • AAVLLPVLLAAP (Rojas et al. 1998)
  • Mut3DPT-C9h
  • VKKKKIKAEIKIYVETLDDIFEQWAHSEDL (de la Torre et al. 2017)
  • Myr-ApoE
  • Myr-LRKLRKRLLR (Tajik-Ahmadabad et al. 2017)
  • New modalities
  • Polycyclic, hairpin, stapled peptides for delivery (Valeur et al. 2017,Waldmann et al. 2017)
  • NF1
  • Stearyl-AGY(PO3)LLGKTNLKALAALAKKIL (Arukuusk et al. 2013)
  • NF51
  • δ-(Stearyl-AGYLLG)OINLKALAALAKKIL (Arukuusk et al. 2013)
  • NF55
  • δ-(Stearyl-AGYLLG)OINLKALAALAKAIL (Freimann et al. 2016)
  • NLS
  • PKKKRKV (Yoneda et al. 1992).
  • NLS-StAx-h
  • stapled RRWPRXILDXHVRRVWR (Dietrich et al. 2017)
  • NoLS
  • KKRTLRKNDRKKRC (Yao et al. 2015)
  • Novicidin
  • KNLRRIIRKGIHIIKKYF (Milosavljevic et al. 2016)
  • NPFSD
  • VLTNENPFSDP (Gong et al. 2016)
  • NYAD-1
  • stapled ITFEDLLDYYGP (Zhang et al. 2008)
  • Oct4-PTD
  • DVVRVWFCNRRQKGKR (Adachi et al. 2017)
  • P007
  • Ac-(RAhxR)4-Ahx-βAla (Greer et al. 2014)
  • P1
  • LRRWSLG (Peng et al. 2017b)
  • P2
  • WKRTLRRL (Peng et al. 2017b)
  • P3
  • YGRKKRRQR (Tan et al. 2006)
  • P7
  • RRMKWKK (Watson et al. 2017)
  • P11
  • YGRKKRRQRRR (Zhao et al. 2011)
  • P11
  • HSDVHK (Bang et al. 2011)
  • P11LRR
  • P11LRR (Li et al. 2010)
  • P14LRR
  • LSTAADMQGVVTDGMASG (Taylor et al. 2009)
  • p18
  • LSTAADMQGVVTDGMASG (Taylor et al. 2009)
  • P21
  • KRKKKGKGLGKKRDPCLRKYK (Dixon et al. 2016)
  • P28
  • LSTAADMQGVVTDGMASGLDKDYLKPDD, Leu50-Asp77 of azurin(Yamada et al. 2016)
  • P28
  • FLHSGTAVTCTYPALTPQWEGSDCTHRL (Signorelli et al. 2017)
  • p53 peptide MO6
  • Stapled TSF*EYWYLL* (Chee et al. 2014)
  • PAF26
  • Ac-rkkwfw (Lopez-Garcia et al. 2002)
  • PAS
  • GKPILFF (Woldetsadik et al. 2017)
  • pCLIP6
  • KVRVRVRVpP(pT)RVRERVK (Chen et al. 2017b)
  • pD-SP5
  • riPRPSPKMGV(pS)VS (Chen et al. 2017b)
  • PenetraMax
  • KWFKIQMQIRRWKNKR, L- and D- (Khafagy el et al. 2015)
  • Penetratin
  • RQIKIWFQNRRMKWKK (Derossi et al. 1994)
  • Pep-1
  • KETWWETWWTEWSQPKKKRKV cysteamide (Morris et al. 1997)
  • pepM
  • KLFMALVAFLRFLTIPPTAGILKRWGTI (Freire et al. 2014)
  • pepR
  • LKRWGTIKKSKAINVLRGFRKEIGRMLNILNRRRR (Freire et al.2014)
  • Pept1
  • PLILLRLLRGQF (Marks et al. 2011)
  • Peptide 599
  • GLFEAIEGFIENGWEGMIDGWYGGGGRRRRRRRRRK(Alexander-Bryant et al. 2015)
  • Pep42
  • Cyclic CTVALPGGYVRVC (Kim et al. 2006)
  • PepNeg
  • SGTQEEY (Neves-Coelho et al. 2017)
  • PepFect6
  • Stearyl-AGYLLGK(εTMQ)INLKALAALAKKIL, PF6 (El-Andaloussiet al. 2011)
  • PepFect14
  • Stearyl- AGYLLGKLLOOLAAAALOOLL (Ezzat et al. 2011)
  • PG1
  • RGGRLCYCRRRFCVCVGR (Liu et al. 2013b)
  • pHLIP
  • AEQNPIY-WARYADWLFTTPLLLLDLALLV-DADEGT (Andreevet al. 2010)
  • PHPs
  • H6-H10 peptides (Kimura et al. 2017)
  • PIP1
  • RXRRXRRXRIKILFQNRRMKWKK (Ivanova et al. 2008)
  • Pip5e
  • RXRRBRRXRILFQYRXRBRXRB (Betts et al. 2012)
  • Pip6a
  • Ac-RXRRBRRXRYQFLIRXRBRXRB (Lehto et al. 2014)
  • POD
  • CGGG(ARKKAAKA)4 (Dasari et al. 2017)
  • PR9
  • FFLIPKG-R9 (Liu et al. 2013a)
  • PTD
  • YARVRRRGPRRR (Dong et al. 2016)
  • PTD3
  • R9-ETWWETWWTEW (Kizaka-Kondoh et al. 2009)
  • PTD4
  • YARAAARQARA (McCusker et al. 2007)
  • Poly-Arg
  • Most popular R7 - R12 (Mitchell et al. 2000, Futaki, 2006)
  • pVEC
  • LLIILRRRIRKQAHAHSK (Elmquist et al. 2001)
  • Pyrrhocoricin
  • VDKGSYLPRPTPPRPIYNRN (Otvos et al. 2000)
  • R4K1
  • Stapled Ac-RRRRKS*LHRS*LQDS (Speltz et al. 2018)
  • R6dGR
  • R6dGR (Wang et al. 2017)
  • R8
  • R8 (Wender et al. 2001)
  • R8-dGR
  • R8dGR (Liu et al. 2016b)
  • R9-H4A2
  • Ac-YR9-HAHAHH (Okitsu et al. 2017)
  • R6W3
  • R6W3 (Bechara et al. 2013)
  • R10W6
  • R10W6 (Bechara et al. 2013)
  • RA9
  • RRAARRARR (Alhakamy et al. 2013)
  • RALA
  • WEARLARALARALARHLARALARALRACEA (McCarthy et al.2014)
  • RDP
  • CKSVRTWNEI IPSKGCLRVG GRCHPHVNGG GRRRRRRRRC(Xiao et al. 2017)
  • REDV
  • REDV (Yang et al. 2016)
  • RF
  • GLKKLARLFHKLLKLGC (Yang et al. 2014)
  • cRGDfC
  • Cyclic RGDfC (Wada et al. 2017)
  • iRGD
  • Cyclic CRGDKGPDC (Peng and Kopecek, 2015)
  • RGE
  • RGERPPR (Yu et al. 2017)
  • RH9
  • RRHHRRHRR (Alhakamy et al. 2013)
  • RL9
  • RRLLRRLRR (Alhakamy et al. 2013)
  • RL16
  • RRLRRLLRRLLRRLRR (Joanne et al. 2009)
  • RT53
  • RQIKIWFQNRRMKWKKAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKT (Jagot-Lacoussiere et al. 2016)
  • RTP004
  • RKKRRQRRRG-K15-GRKKRRQRRR) (Lee et al. 2015a)
  • RV24
  • RRRRRRRRRGPGVTWTPQAWFQWV (Lo and Wang, 2012)
  • RVG
  • YTIWMPENPRPGTPCDIFTNSRGKRASNG (Kumar et al. 2007)
  • RVG-9R
  • YTIWMPENPRPGTPCDIFTNSRGKRASNGGGGRRRRRRRRR(Rassu et al. 2017)
  • RVG29
  • YTIWMPENPRPGTPCDIFTNSRGKRASNGGGGRRRRRRRRR(Villa-Cedillo et al. 2017)
  • RW9
  • RRWWRRWRR (Alhakamy et al. 2013)
  • RW16
  • RRWRRWWRRWWRRWRR (Jobin et al. 2013)
  • (RXR)4
  • (R-Ahx-R)4 (Saleh et al. 2010)
  • (rXr)4
  • (r-Ahx-r)4 (Vij et al. 2016b)
  • S155
  • VKKKKIKREI-KIAAQRYGRELRRMADEFHV (Haidar et al. 2017)
  • S4(13)-PV
  • ALWKTLLKKVLKAPKKKRKV (Mano et al. 2007)
  • SAP
  • VRLPPPVRLPPPVRLPPP (Pujals et al. 2006)
  • SAP(E)
  • VELPPPVELPPPVELPPP (Martin et al. 2011)
  • all-D-SAP
  • (vrlppp)3 (Pujals et al. 2007)
  • SAPSp-lipo
  • stearyl-GGGGHGAHEHAGHEHAAGEHHAHE (Suzuki et al. 2017)
  • SAR6EW
  • SAR6EW (Im et al. 2017)
  • sC18
  • GLRKRLRKFRNKIKEK (Oren et al. 1999)
  • (sC18)2
  • (GLRKRLRKFRNKIKEK)2 (Gronewold et al. 2017)
  • SMTP motif
  • LRLLR (Fuselier and Wimley, 2017)
  • SPACE
  • Cyclic ACTGSTQHQCG (Hsu and Mitragotri, 2011)
  • SRCRP2-11
  • GRVEVLYRGSW (Tuttolomondo et al. 2017)
  • STR-KV
  • H3K3V6 (Pan et al. 2016)
  • SS-02
  • Dmt-r-FK (Alta et al. 2017)
  • SS-20
  • F-r-FK (Alta et al. 2017)
  • SS-31
  • r-Dmt-KF (Zhao et al. 2005)
  • SynB1
  • RGGRLSYSRRRFSTSTGR (Rousselle et al. 2000)
  • T2
  • LVGVFH (Kumar et al. 2012)
  • Tat(49-57)
  • RKKRRQRRR (Vives et al. 1997a)
  • Tat(48-60)
  • GRKKRRQRRRPPQ (Vives et al. 1997b)
  • Tat(44-57)
  • CGISYGRKKRRQRRR (Niesner et al. 2002)
  • Tat(37-72)
  • CFITKALGISYGRKKRRQRRRPPQGSQT-HQVSLSKQ (Fawell et al.1994)
  • Tat analog
  • GRKKRRQR (Nguyen et al. 2008)
  • Tat-LK15
  • GRKKRRQR (Nguyen et al. 2008)
  • TCTP
  • MIIFRALISHKK (Bae et al. 2016)
  • TD-1
  • ACSSSPSKHCG (Chen et al. 2006)
  • TD2.2
  • SYWYRIVLSRTGRNGRLRVGRERPVLGESP (Heffernan et al. 2012)
  • TH peptide
  • GYLLGHINLHHLAHL-Aib-HHIL (Chen et al. 2017a)
  • TM2
  • PKKGSKKAVTKAQKKDGA (Kochurani et al. 2015)
  • Transportan
  • GWTLNSAGYLLGKINLKALAALAKKIL, TP (Pooga et al. 1998)
  • TP10
  • AGYLLGKINLKALAALAKKIL (Soomets et al. 2000)
  • TPk
  • VRRFkWWWkFLRR (Bahnsen et al. 2015)
  • Tpl
  • KWCFRVCYRGICYRRCRGK (Jain et al. 2015)
  • TPP
  • TKDNNLLGRFELSG (Gehrmann et al. 2014)
  • TT1
  • CKRGARSTA (Paasonen et al. 2016)
  • vAMP 059
  • INWKKWWQVFYTVV (Dias et al. 2017)
  • vCPP 0769
  • RRLTLRQLLGLGSRRRRRSR (Dias et al. 2017)
  • vCPP 2319
  • WRRRYRRWRRRRRWRRRPRR (Dias et al. 2017)
  • VDAC(1-26)
  • MAVPPTYADLGKSARDVFTKGYGFGL (Smilansky et al. 2015)
  • VP22
  • NAATATRGRSAASRPTQRPRAPARSASRPRRPVQ (Elliott andO’Hare, 1997)
  • V peptide
  • TVDNPASTTNKDKLFAVRK (Manosroi et al. 2014)
  • VT5
  • DPKGDPKGVTVTVTVTVTGKGDPKPD (Oehlke et al. 1997)
  • W(RW)4
  • W(RW)4 (Nasrolahi Shirazi et al. 2013)
  • Xentry
  • LCLR (Montrose et al. 2014)
  • X-pep
  • MAARLC (Adachi et al. 2017)
  • YKA
  • YKALRISRKLAK (Desai et al. 2014)
  • YTA2
  • YTAIAWVKAFIRKLRK (Lindgren et al. 2006)
  • YTA4
  • IAWVKAFIRKLRKGPLG (Lindgren et al. 2006)
  • Z2
  • FWIGGFIKKLKRSKLA (Chen et al. 2017c)
  • Z3
  • FKIKKFIGGLWRSKLA (Chen et al. 2017c)
  • Z12
  • KRYKNRVASRKCRAKFKQLLQHYREVAAAKSSENDRLRLLLK (Derouazi et al. 2015)
  • ZXR-1
  • FKIGGFIKKLWRSKLA (Chen et al. 2017c)
备注：Ac=acetyl；Ahx或X=aminohexanoic acid；Aib=aminoisobutyric acid；B=β-alanine；Bpg=bishomopropargylglycine；Dmt=dimethyltyrosine；O=ornithine；
pT=phosphoryl-Thr；pS=phosphoryl-Ser；Φ=l-2-naphthylalanine；ri=retro-inverso；*=staple tethering site。

肽研生物专注多肽合成，多肽修饰，致力于提供更优质的产品和更优秀的服务.

订购热线：

  • 手机：19941518170

  • 邮箱：sales@typeptide.com

  • QQ：2178255659

  • 微信：19941518170

  • 地址：南京市江北新区天圣路22号F栋12楼

Copyright ©2023 南京肽研生物科技有限公司
苏ICP备2025190410号-1

扫描添加微信联系我们
支持喀斯玛平台下单
支持瑞竞平台下单

友情连接：

百度

LinkIn

小木虫

ChemicalBook